Opportunity Information: Apply for RFA CA 18 015
The NCI Community Oncology Research Program (NCORP) Research Bases funding opportunity (RFA-CA-18-015) is a National Cancer Institute cooperative agreement (UG1, clinical trial required) that supports organizations serving as "Research Bases" within NCORP, a national, community-focused cancer research network. The central purpose is to expand and strengthen the ability to design and run cancer-related clinical trials and other human subjects studies in real-world community settings, while also ensuring that research addresses prevention, screening, symptom management, survivorship, and how cancer care is delivered. Unlike grants where the awardee operates largely independently, this cooperative agreement structure reflects substantial NCI programmatic involvement, meaning awardees are expected to work closely with NCI to plan, conduct, and oversee the research portfolio.
NCORP as a whole is built to bring high-quality cancer research beyond large academic medical centers and into the places where many patients actually receive care. Within that system, Research Bases function as the scientific and operational hubs. They are responsible for designing and conducting cancer clinical trials and care delivery research studies, coordinating study implementation across participating community sites, and handling core research operations such as data management, statistical analysis, and reporting results. A key element of this announcement is that Research Bases are expected to support studies across the cancer continuum, including cancer prevention, cancer control, screening, and care delivery research, as well as quality-of-life components that may be embedded within treatment trials. In practical terms, this means the funded groups are not only expected to propose and run trials, but also to build the infrastructure and expertise needed to manage multi-site studies and produce analyzable, publishable outcomes.
A major emphasis of NCORP is equitable participation and relevance of research for populations that have historically been underrepresented in clinical studies or that face unique barriers to care. The announcement highlights the expectation that Research Bases incorporate the specific research needs of diverse communities into study design and execution, including adolescents and young adults (AYAs), older adults, racial and ethnic minority groups, sexual and gender minority populations, and rural residents. Beyond simply acknowledging these groups, the program expects intentional efforts to enhance their participation, which typically implies thoughtful eligibility criteria, recruitment strategies, culturally and linguistically appropriate engagement, and site support that makes enrollment feasible for community clinics and their patients.
This FOA also positions NCORP as a bridge to the National Clinical Trials Network (NCTN). One of the program goals is to enhance patient and provider access to treatment and imaging trials run through NCTN by leveraging NCORP's community footprint. Research Bases therefore operate in an ecosystem where they may support or align with NCTN studies and help ensure that patients treated in community settings can access advanced treatment and imaging trials without needing to travel to distant academic centers. At the same time, NCORP explicitly integrates cancer disparities research into the community network, so Research Bases are expected to embed disparity-relevant questions and methods into their trial portfolios and study operations, rather than treating disparities as a separate or optional topic.
Structurally, NCORP is described as having three components, each covered by a separate funding opportunity announcement: NCORP Research Bases (this FOA), NCORP Community Sites, and NCORP Minority/Underserved Community Sites. Research Bases differ from community sites in that they lead the research agenda, develop protocols, coordinate the research network functions tied to those protocols, and serve as the analytic and reporting engine. Community sites, in contrast, are generally the locations where patients are enrolled and study procedures occur. Minority/Underserved Community Sites are similarly focused on enrollment and implementation but with an emphasis on serving populations that are minority or otherwise underserved. The interplay among these components is core to NCORP's model: Research Bases supply study leadership and infrastructure, while sites supply broad access, diversity, and real-world care settings.
From an administrative perspective, the opportunity is offered by the Department of Health and Human Services through the National Institutes of Health, specifically NCI. It is categorized as discretionary funding and uses the cooperative agreement mechanism. Eligible applicants are broad and include various levels of government (state, county, city/township, special districts), public and private institutions of higher education, federally recognized tribal governments and other tribal organizations, public housing authorities/Indian housing authorities, a range of nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities), for-profit organizations (other than small businesses), small businesses, and other entities as described in the full eligibility text. The FOA indicates an expected number of awards of seven. An explicit award ceiling is not specified in the provided summary (listed as 0), which typically means applicants need to consult the full FOA for budget expectations, allowable costs, and any limits or guidance that may be stated elsewhere.
In short, this opportunity funds a small number of organizations to serve as NCORP Research Bases that design, coordinate, and analyze community-based cancer clinical trials and care delivery research, with strong expectations around inclusivity, relevance to diverse and underserved populations, connection to national treatment and imaging trials, and robust data management and reporting. The overall intent is to generate practical, generalizable evidence about cancer prevention and care in the settings where most patients receive treatment, while improving access to trials and embedding cancer disparities research directly into the community research infrastructure.Apply for RFA CA 18 015
- The Department of Health and Human Services, National Institutes of Health in the education, health sector is offering a public funding opportunity titled "NCI Community Oncology Research Program (NCORP) Research Bases (UG1 Clinical Trial Required)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393, 93.394, 93.395, 93.399.
- This funding opportunity was created on Jun 13, 2018.
- Applicants must submit their applications by Aug 31, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 7 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs)
1) What is the NCORP Research Bases funding opportunity (RFA-CA-18-015)?
This opportunity is a National Cancer Institute (NCI) cooperative agreement (UG1) that funds organizations to serve as "Research Bases" within the NCI Community Oncology Research Program (NCORP). Research Bases function as the scientific and operational hubs of a national, community-focused cancer research network.
2) Which agency is offering this funding opportunity?
The opportunity is offered by the U.S. Department of Health and Human Services through the National Institutes of Health (NIH), specifically the National Cancer Institute (NCI).
3) What type of award mechanism is used?
The award uses a cooperative agreement mechanism (UG1). The FOA also notes that a clinical trial is required.
4) What does it mean that this is a cooperative agreement?
In a cooperative agreement, the NCI has substantial programmatic involvement. Awardees are expected to work closely with NCI to plan, conduct, and oversee the research portfolio rather than operating entirely independently.
5) What is the central purpose of funding NCORP Research Bases?
The central purpose is to expand and strengthen the ability to design and run cancer-related clinical trials and other human subjects studies in real-world community settings, and to ensure research addresses key topics across the cancer continuum (prevention, screening, symptom management, survivorship, and cancer care delivery).
6) What is NCORP, in practical terms?
NCORP is a national cancer research network designed to bring high-quality cancer research beyond large academic medical centers and into community settings where many patients receive care. It emphasizes research that is feasible and relevant in real-world practice environments.
7) What is a "Research Base" within NCORP?
A Research Base is the scientific and operational hub responsible for leading research within NCORP. Research Bases design and conduct studies, coordinate study implementation across multiple community sites, and provide core operational capabilities such as data management, statistical analysis, and reporting results.
8) How are NCORP Research Bases different from NCORP Community Sites?
Research Bases lead the research agenda, develop protocols, coordinate network functions tied to those protocols, and serve as the analytic and reporting engine. Community Sites are generally where patients are enrolled and study procedures occur.
9) How are NCORP Research Bases different from Minority/Underserved Community Sites?
Minority/Underserved Community Sites focus on enrollment and implementation in settings that serve minority or otherwise underserved populations. Research Bases still provide study leadership, coordination, infrastructure, and analytics; sites provide access to patients and real-world clinical settings.
10) What kinds of research are Research Bases expected to support?
Research Bases are expected to support studies across the cancer continuum, including cancer prevention, cancer control, screening, and care delivery research. They may also support quality-of-life components that can be embedded within treatment trials.
11) Are clinical trials required under this FOA?
Yes. The opportunity is identified as a UG1 cooperative agreement with "clinical trial required."
12) Does this funding only support treatment trials?
No. The description emphasizes a broad portfolio that can include prevention, screening, symptom management, survivorship, and cancer care delivery research, in addition to treatment-related research and quality-of-life components.
13) What operational responsibilities do Research Bases typically carry?
Research Bases are expected to coordinate multi-site study implementation and handle core research operations such as data management, statistical analysis, and reporting results, with the goal of producing analyzable and publishable outcomes.
14) Why is the community setting emphasized in this program?
The program is designed to generate practical, generalizable evidence in the settings where many patients receive care, rather than limiting research to large academic centers.
15) How does NCORP address equitable participation in research?
The FOA emphasizes intentional efforts to ensure research is relevant to and inclusive of populations that have historically been underrepresented in clinical studies or face barriers to care. This includes designing and executing studies with the needs of diverse communities in mind and enhancing participation.
16) Which populations are specifically highlighted as priorities for inclusion?
The announcement highlights adolescents and young adults (AYAs), older adults, racial and ethnic minority groups, sexual and gender minority populations, and rural residents.
17) What kinds of approaches are implied for improving participation of underserved or underrepresented groups?
While the summary does not prescribe a fixed set of methods, it indicates expectations around intentional efforts such as thoughtful eligibility criteria, recruitment strategies, culturally and linguistically appropriate engagement, and site support that makes enrollment feasible for community clinics and their patients.
18) How does this program relate to cancer disparities research?
NCORP explicitly integrates cancer disparities research into the community network. Research Bases are expected to embed disparity-relevant questions and methods into their trial portfolios and study operations rather than treating disparities as a separate or optional topic.
19) What is the relationship between NCORP and the National Clinical Trials Network (NCTN)?
NCORP is positioned as a bridge to NCTN. One goal is to enhance patient and provider access to NCTN treatment and imaging trials by leveraging NCORP's community footprint, helping patients access advanced trials without needing to travel to distant academic centers.
20) What role might a Research Base play with respect to NCTN studies?
Research Bases operate in an ecosystem where they may support or align with NCTN studies and help ensure that community-based patients can access treatment and imaging trials through the broader national clinical trials infrastructure.
21) How many awards are expected under this funding opportunity?
The FOA indicates an expected number of awards of seven.
22) Is there an award ceiling or maximum budget listed in the provided summary?
No explicit award ceiling is specified in the provided summary (it is listed as 0). This typically means applicants need to consult the full FOA for budget expectations, allowable costs, and any limits or guidance that may be stated elsewhere.
23) What is the funding category for this opportunity?
The opportunity is categorized as discretionary funding.
24) Who is eligible to apply based on the information provided?
Eligibility is described as broad and includes various levels of government (state, county, city/township, and special districts), public and private institutions of higher education, federally recognized tribal governments and other tribal organizations, public housing authorities/Indian housing authorities, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities), for-profit organizations (other than small businesses), small businesses, and other entities as described in the full eligibility text.
25) What is the main value a funded Research Base is expected to deliver?
A funded Research Base is expected to deliver leadership and infrastructure for designing, coordinating, and analyzing community-based clinical trials and human subjects studies, producing results that are practical, generalizable, and publishable, while improving access to trials and embedding disparities-focused research directly into community research operations.
26) How do Research Bases and community sites work together in NCORP?
The model is collaborative: Research Bases provide study leadership, protocol development, coordination, and analytics, while community sites provide broad access to patients, diversity of participants, and real-world care environments where studies are implemented.
27) What outcomes is this program ultimately trying to achieve?
The overall intent is to strengthen community-based cancer research capacity, improve access to trials, ensure relevance to diverse and underserved populations, and generate evidence about prevention and cancer care delivery in settings where most patients are treated.
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