Opportunity Information: Apply for CDC RFA EH22 2201
The grant opportunity "Enhancing Disease Detection in Newborns: Building Capacity in Public Health Laboratories" (CDC RFA EH22 2201) is a CDC cooperative agreement designed to help state and territorial newborn screening laboratories strengthen their ability to test for conditions recommended for screening by the U.S. Department of Health and Human Services Advisory Committee on Heritable Disorders in Newborns and Children (ACHDNC). The central purpose is to expand and modernize public health laboratory capacity so more jurisdictions can add recommended conditions to their newborn screening panels and be better positioned to adopt additional conditions in the future, including those that individual states may choose to add through state advisory committees or legislation.
The public health problem this program focuses on is straightforward but high impact: many serious disorders cannot be recognized at birth through routine clinical observation because symptoms may not appear until damage has already begun. Newborn screening, particularly testing performed on dried blood spot specimens, is meant to catch these conditions early enough that treatment can begin promptly. The program description emphasizes that early detection and intervention can prevent disability and save lives, and that improving laboratory capability directly translates into more infants being screened appropriately, identified when they screen positive, and referred for confirmatory testing and treatment.
Funding is planned over a 2-year project period, with CDC intending to support up to eight state or territorial newborn screening laboratories. The expected maximum award amount is $500,000 per award (award ceiling), and the funding mechanism is a cooperative agreement, meaning CDC anticipates substantial involvement beyond simply issuing funds. In practice, this collaborative model signals that recipients should expect ongoing technical partnership with CDC, coordination around implementation challenges, and shared work to strengthen program quality and consistency across jurisdictions.
A major emphasis of the opportunity is implementation readiness for ACHDNC-recommended conditions. This commonly involves labs acquiring or upgrading instrumentation, validating new assays, establishing quality control and proficiency testing practices, training staff, updating standard operating procedures, and coordinating with clinical and follow-up partners so that positive screens lead to timely confirmatory testing and care. The opportunity also explicitly highlights improving the overall quality of newborn screening testing in the United States, including work related to data harmonization. Data harmonization generally points to making laboratory and program data more consistent and comparable across states, which supports better quality monitoring, smoother reporting, improved timeliness tracking, and stronger public health understanding of screening outcomes.
Administratively, the opportunity was issued by the Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), specifically within NCEH, and is listed under CFDA 93.065. It falls under the discretionary funding category and the health funding activity area. Eligibility is listed as unrestricted (open broadly), although applicants are expected to align with any clarifications in the official eligibility text; given the stated intent and activities, the practical target audience is state and territorial newborn screening laboratories. The notice was created on March 9, 2022, with an original application deadline of May 9, 2022, and electronic submissions were due by 11:59 pm Eastern Time on the closing date.
Overall, the opportunity is best understood as an effort to close implementation gaps between national recommendations and state-level testing reality. By investing in laboratory capacity, quality improvements, and shared approaches to data and performance, CDC aims to increase the number of newborns who receive comprehensive screening aligned with recommended panels and to ensure that when a condition is detected, the pathway from screening to diagnosis to treatment works quickly and reliably.Apply for CDC RFA EH22 2201
- The Department of Health and Human Services, Centers for Disease Control - NCEH in the health sector is offering a public funding opportunity titled "Enhancing Disease Detection in Newborns: Building Capacity in Public Health Laboratories" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.065.
- This funding opportunity was created on Mar 09, 2022.
- Applicants must submit their applications by May 09, 2022 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- The number of recipients for this funding is limited to 8 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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